Janumet (Sitagliptin and Metformin): How It Is Taken

Janumet (sitagliptin and metformin tablets)

Sitagliptin with metformin in one tablet, taken with meals, to lower blood sugar in adults with type 2 diabetes.

We do not currently have Janumet, so there is no price list. It is prescription-only in Australia. The type 2 diabetes medicines we can supply are listed on our diabetes page.

Janumet combines sitagliptin and metformin in one tablet for type 2 diabetes — and it is not currently available from us. This page explains what it is and how it is taken; the medicines we can supply are listed in our guide to type 2 diabetes medicines.

What is Janumet?

Each tablet contains sitagliptin 50 mg with metformin 500, 850 or 1000 mg, and it is used to lower blood sugar levels in adults with type 2 diabetes (Janumet CMI). It puts two medicines in one tablet: metformin, usually the first medicine for type 2 diabetes (healthdirect), and sitagliptin, a DPP-4 inhibitor — the medicine in Januvia.

How is Janumet taken?

With meals, to lower the chance of an upset stomach, at about the same time each day (Janumet CMI). How many tablets a day, and which strength, is your doctor's decision.

What is the lactic acidosis warning?

Metformin can rarely cause lactic acidosis, a serious build-up of acid in the blood. The Janumet leaflet says to stop taking it and get emergency care if you have symptoms such as feeling very weak and tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, or diarrhoea (Janumet CMI).

Can Janumet cause low blood sugar?

Low blood sugar can happen when Janumet is used together with a sulfonylurea or with insulin, so your doctor may lower those doses (Janumet CMI).

What are the side effects?

They include symptoms of infection, nausea, headache and muscle aches; serious ones — allergic reactions, pancreatitis (severe, persistent stomach pain), skin erosion and kidney problems — need a doctor straight away (Janumet CMI).

Can you get Janumet from us?

No. We do not currently have Janumet or Januvia, so there is no price list for them. The type 2 diabetes medicines we can supply, and their status on the Australian register, are set out in the diabetes medicines guide.

Sources

Janumet CMI (Merck Sharp & Dohme (Australia), prepared July 2026)
healthdirect — Metformin

Janumet — common questions

Sitagliptin 50 mg with metformin 500, 850 or 1000 mg in each tablet, used to lower blood sugar levels in adults with type 2 diabetes.

Yes — with meals, to lower the chance of an upset stomach, at about the same time each day.

If you have symptoms of lactic acidosis — feeling very weak and tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, or diarrhoea — stop taking it and get emergency care.

Not at the moment: we do not currently have Janumet or Januvia.

Reviews

David 2024-04-07 · 4.0/5

Janumet is a bit more expensive than some other medications, but I believe it's worth the cost because it effectively manages my blood sugar without causing major side effects. I do wish it were more affordable, but the results make it worthwhile.

Emma 2024-03-12 · 5.0/5

My doctor recommended Janumet because of its long-term benefits in managing blood sugar and reducing the risk of diabetes complications. I feel confident in this treatment and hope it will help prevent future issues with my heart and kidneys.

Sophia 2024-02-28 · 5.0/5

I take several medications for my blood pressure and cholesterol, so I was concerned about potential interactions. Fortunately, Janumet has worked well with my other meds, and I haven't experienced any negative interactions. My doctor assured me it's a safe choice.

Alice 2024-02-10 · 5.0/5

I've been on Janumet for about six months now, and my blood sugar levels have significantly improved. My HbA1c dropped from 8.2% to 6.9%, and my daily glucose readings are much more stable. This medication has really helped me get my diabetes under control.

Linda 2024-01-22 · 5.0/5

One of the things I appreciate about Janumet is that it hasn't caused any weight gain. In fact, I've even lost a few pounds since starting it. This has been a great bonus, as I was worried about gaining weight with a new medication.

Mark 2023-12-15 · 4.0/5

At first, I experienced some mild stomach discomfort and diarrhea when I started taking Janumet. However, these side effects eased after the first couple of weeks. Now I don't notice any issues, and I'm feeling much better overall.

John 2023-11-05 · 5.0/5

Taking Janumet is straightforward and fits easily into my daily routine. I like that it's just one pill instead of taking two separate medications. The dosing is convenient, and I haven't had any issues with remembering to take it.

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